Organic Chemistry – J. Clayden, N. Greeves, S. Warren, P. Wothers – 1st Edition


A first and second year undergraduate organic chemistry textbook, specifically geared to British and European courses and courses offered in better schools in North America. The emphasis is on clarity and understanding, with very careful explanations of difficult concepts, many examples related to everyday life, and a fresh and student-friendly writing style.

The book accompanies the beginner in organic chemistry from the structure of the molecules, over NMR up to the topics for advanced, like heterocycles and asymmetrical synthesis. A typical arrangement of functional groups as seen in older text books does not occur. Thus, rather mechanisms and concepts of organic chemistry with rising difficulties are explained. Therefore it can be seen , that a certain mechanism (e.g. the addition to a carbonyl group) can be applied to different functional groups.

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  • 1 What is organic chemistry?
    2 Organic structures
    3 Determining organic structures
    4 Structure of molecules
    5 Organic reactions
    6 Nucleophilic addition to the carbonyl group
    7 Delocalization and conjugation
    8 Acidity, basicity, and pKa
    9 Using organometallic reagents to make C-C bonds
    10 Conjugate addition
    11 Proton nuclear magnetic resonance
    12 Nucleophilic substitution at the carbonyl (C=O) group
    13 Equilibria, rates, and mechanisms: summary of mechanistic principles
    14 Nucleophilic substitution at C=O with loss of carbonyl oxygen
    15 Review of spectroscopic methods
    16 Stereochemistry
    17 Nucleophilic substitution at saturated carbon
    18 Conformational analysis
    19 Elimination reactions
    20 Electrophilic addition to alkenes
    21 Formation and reactions of enols and enolates
    22 Electrophilic aromatic substitution
    23 Electrophilic alkenes
    24 Chemoselectivity: selective reactions and protection
    25 Synthesis in action
    26 Alkylation of enolates
    27 Reactions of enolates with aldehydes and ketones: the aldol reaction
    28 Acylation at carbon
    29 Conjugate addition of enolates
    30 Retrosynthetic analysis
    31 Controlling the geometry of double bonds
    32 Determination of stereochemistry by spectroscopic
    33 Stereoselective reactions of cyclic compounds
    34 Diastereoselectivity
    35 Pericyclic reactions 1: cycloadditions
    36 Pericyclic reactions 2: sigmatropic and electrocyclic reactions
    37 Rearrangements
    38 Fragmentation
    39 Radical reactions
    40 Synthesis and reactions of carbenes
    41 Determining reaction mechanisms
    42 Saturated heterocycles and stereoelectronics
    43 Aromatic heterocycles 1: structures and reactions
    44 Aromatic heterocycles 2: synthesis
    45 Asymmetric synthesis
    46 Organo-main-group chemistry I: sulfur
    47 Organo-main-group chemistry II: boron, silicon, and tin
    48 Organometallic chemistry
    49 The chemistry of life
    50 Mechanisms in biological chemistry
    51 Natural products
    52 Polymerization
    53 Organic chemistry today
  • Citation

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